In vitro amoebicidal activity of Salvia staminea and Salvia caespitosa on Acanthamoeba castellanii and their cytotoxic potentials on corneal cells.

Goze, Ismihan; Alim, AHMET; DAĞ, ŞEKER; TEPE, Bektaş; Polat, ZÜBEYDA

doi:10.1089/jop.2008.0132

In vitro amoebicidal activity of Salvia staminea and Salvia caespitosa on Acanthamoeba castellanii and their cytotoxic potentials on corneal cells.

Goze I., Alim A., DAĞ Ş., TEPE B., Polat Z.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, cilt.25, sa.4, ss.293-8, 2009 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 25 Sayı: 4
Basım Tarihi: 2009
Doi Numarası: 10.1089/jop.2008.0132
Dergi Adı: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.293-8
Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background/Aims: Amoebic keratitis is difficult to treat with total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments. We investigated the in vitro effectiveness of methanolic extract of Salvia staminea and Salvia caespitosa against Acanthamoeba castellanii, as well as their cytotoxicity on corneal cells in vitro.