Potassium-Tertiary Butoxide-Assisted Addition of Thioglicolic Acid to Chalcone Derivatives Under Solvent-Free Conditions


Ceylan M., Gurdere M. B. , Gezegen H. , Budak Y.

SYNTHETIC COMMUNICATIONS, cilt.40, ss.2598-2606, 2010 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 40
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1080/00397910903291129
  • Dergi Adı: SYNTHETIC COMMUNICATIONS
  • Sayfa Sayıları: ss.2598-2606

Özet

A series of chalcone derivatives containing thioglicolic acid (4a-j) was prepared by addition of thioglicolic acid to the chalcones (3a-j) in the presence of KOt-Bu under solvent-free conditions. The mechanistic pathway of the reaction can be explained by the Michael-type addition of thioglicolic acid to chalcone derivatives (3a-j).