Role of D-1/D-2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats


ÖZDEMİR E. , BAĞÇİVAN İ. , GÜRSOY S.

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.13, ss.119-125, 2013 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 13 Konu: 2
  • Basım Tarihi: 2013
  • Dergi Adı: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Sayfa Sayıları: ss.119-125

Özet

While opioid receptors have been implicated in the development of tolerance, the subsequent mechanisms involved in these phenomena have not been completely understood. The purpose of this study was to investigate effects of D-1/D-2 dopamine receptors antagonist perphenazine on morphine analgesia and tolerance in rats.