The importance of SII and FIB-4 scores in predicting mortality in idiopathic pulmonary fibrosis patients

KOYUN G. B., BERK S., DOĞAN Ö. T.

Clinical Biochemistry, cilt.131-132, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131-132
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.clinbiochem.2024.110789
  • Dergi Adı: Clinical Biochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database
  • Anahtar Kelimeler: FIB-4, SII, İdiopathic pulmonary fibrosis
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Introduction: Quick and simple parameters are needed to predict mortality in patients with idiopathic pulmonary fibrosis (IPF). In this way, risky patients will have the opportunity to receive early and effective treatment. In this study, we examined whether the Fibrosis-4 index (FIB-4) and systemic immune inflammation index (SII) are associated with mortality in IPF patients. Materials and methods: The study was designed retrospectively. 100 patients diagnosed with IPF were included in the study. Variables between living patients and deceased patients were examined. Results: Out of a total of 100 patients, 67 were divided into the surviving group and 33 into the non-surviving group. In multivariate analysis, high FIB-4 and SII values were significantly associated with an increased risk of death. Conclusion: FIB-4 and SII are parameters that can predict mortality in IPF patients. In this way, IPF patients with high mortality risk will be identified earlier and more effective methods will be used in follow-up and treatment.