Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs

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DOĞAN H. O., Ersan E. E., AYDIN H., Erdogan S., ERŞAN S., Alisik M., ...Daha Fazla

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, cilt.16, sa.1, ss.39-45, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.9758/cpn.2018.16.1.39
  • Dergi Adı: CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.39-45
  • Anahtar Kelimeler: Schizophrenia, Thiols, Disulfides, Antipsychotics, TOTAL ANTIOXIDANT STATUS, TOTAL OXIDANT STATUS, MEMBRANE-LIPID PEROXIDATION, OXIDATIVE STRESS INDEX, PSYCHIATRIC-DISORDERS, GLUTATHIONE LEVELS, RAT-BRAIN, EXPRESSION, BLOOD, OLANZAPINE
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Objective: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs on oxidative markers in schizophrenia, adequate information is not available on these issues. The aim of this study is to determine the changes in oxidative status and thiol disulfide homeostasis in schizophrenic patients using atypical antipsychotic drugs.