Does mammalian target of rapamycin or sestrin 1 protein signaling have a role in bone fracture healing?


Pazarci Ö., Doğan H. O. , Kilinç S. , Çamurcu I.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.49, no.6, pp.1774-1778, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.3906/sag-1809-117
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.1774-1778

Abstract

Background/aim: Fracture healing is a complex physiological process that involves a well-orchestrated series of biological events. The mammalian target of rapamycin (mTOR) and sestrin 1 (SESN 1) play a central role in cell metabolism, proliferation, and survival. The aim of our study is to present serum mTOR and SESN 1 levels by comparing patients with or without bone fractures. It is also a guide for further research on the roles of these proteins in fracture healing.