Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis.


Polat Z. , Walochnik J., Obwaller A., VURAL ÖZEÇ A. , DURSUN A. , ARICI M. K.

Clinical & experimental ophthalmology, cilt.42, ss.151-8, 2014 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 42 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/ceo.12120
  • Dergi Adı: Clinical & experimental ophthalmology
  • Sayfa Sayıları: ss.151-8

Özet

BackgroundIn this study, a series of compounds - miltefosine, polyhexamethylene biguanide, chlorhexidine and propamidine isethionate - and combinations of the latter three agents with miltefosine were prepared and used in a rat model for the topical treatment of Acanthamoeba keratitis.