No association of polymorphisms in the glutathione S-transferase genes with pre-eclampsia, eclampsia and HELLP syndrome in a Turkish population.

Cetin, M; Pinarbasi, ERGÜN; Percin, FE; Akgun, E; Percin, S; Pinarbasi, H; Gurlek, F; Cetin, A

doi:10.1111/j.1447-0756.2005.00281.x

No association of polymorphisms in the glutathione S-transferase genes with pre-eclampsia, eclampsia and HELLP syndrome in a Turkish population.

Cetin M., Pinarbasi E., Percin F., Akgun E., Percin S., Pinarbasi H., ...Daha Fazla

The journal of obstetrics and gynaecology research, cilt.31, sa.3, ss.236-41, 2005 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 31 Sayı: 3
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1447-0756.2005.00281.x
Dergi Adı: The journal of obstetrics and gynaecology research
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.236-41
Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Aim: There is substantial evidence that genetic factors play a role in pre-eclampsia. The aim of this study was to determine whether genetic variability in the encoding of genes for glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) contributes to individual differences in susceptibility to pre-eclampsia, eclampsia, or hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome).