Antifibrotic Effect of Boric Acid in Rats with Epidural Fibrosis


BOZKURT H. , Bektasoglu P. K. , Borekci A., Ozturk O. C. , Kertmen H., Egilmez R., ...More

WORLD NEUROSURGERY, vol.122, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 122
  • Publication Date: 2019
  • Doi Number: 10.1016/j.wneu.2018.10.187
  • Title of Journal : WORLD NEUROSURGERY

Abstract

BACKGROUND: Epidural fibrosis is a major problem after spine surgery, with some patients having recurrent symptoms secondary to excessive formation of scar tissue resulting in neurologic compression. We used a rat laminectomy model to determine if topical application of boric acid could be helpful in the prevention of epidural fibrosis.