Antifibrotic Effect of Boric Acid in Rats with Epidural Fibrosis

BOZKURT H., Bektasoglu P. K., Borekci A., Ozturk O. C., Kertmen H., Egilmez R., ...Daha Fazla

WORLD NEUROSURGERY, cilt.122, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 122
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.wneu.2018.10.187
  • Dergi Adı: WORLD NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BACKGROUND: Epidural fibrosis is a major problem after spine surgery, with some patients having recurrent symptoms secondary to excessive formation of scar tissue resulting in neurologic compression. We used a rat laminectomy model to determine if topical application of boric acid could be helpful in the prevention of epidural fibrosis.