Sensitive method for determination of benzoic acid in beverages and food samples using air–assisted hydrophobic deep eutectic solvent-based dispersive liquid-liquid microextraction

ALTUNAY N., Lanjwani M. F., Haq H. U., Tuzen M., ELİK A.

Sustainable Chemistry and Pharmacy, cilt.38, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.scp.2024.101464
  • Dergi Adı: Sustainable Chemistry and Pharmacy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Aromatic compounds, Carboxylic acids, Food analysis, Food pollution, Green chemistry, Quality control
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

A simple, reliable and rapid air–assisted hydrophobic deep eutectic solvent-based dispersive liquid–liquid microextraction (AA-HDES-DLLME) was developed for analysis of benzoic acid in various beverages and food samples. The final determination stage was performed via UV–visible spectrophotometry. The key parameters (extraction time, HDES type and volume, dispersant volume, pH and sample volume) of the AA-HDES-DLLME method were optimized in detailed using Box–Behnken design. Analysis of variance was used for statistical analysis. Under the optimized conditions, limit of detection (12.1 μg L−1), limit of quantification (40 μg L−1), linearity range (40–1000 μg L−1), and preconcentration factor (140) were determined. While the accuracy of the AA-HDES-DLLME method was investigated with the standard addition approach, its precision was investigated with intraday/interday studies. The method proved to be effective for routine analytical practice for a wide variety of samples. The novelty of the AA-HDES-DLLME method is that it enables the extraction of benzoic acid without the need for heating or centrifugation steps. In this way, the AA-HDES-DLLME method enabled selective extraction of benzoic acid in a shorter time and using less energy compared to similar studies.