Stimulation of epithelial cell matrix metalloproteinase (MMP-2,-9,-13) and interleukin-8 secretion by fusobacteria

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Gursoy U. K., Koenonen E., Uitto V. -.

ORAL MICROBIOLOGY AND IMMUNOLOGY, vol.23, no.5, pp.432-434, 2008 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 23 Issue: 5
• Publication Date: 2008
• Doi Number: 10.1111/j.1399-302x.2008.00453.x
• Journal Name: ORAL MICROBIOLOGY AND IMMUNOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.432-434
• Sivas Cumhuriyet University Affiliated: Yes

Abstract

Background/aim: Bacterial pathogens involved in periodontal diseases exert their destructive effects primarily by stimulating the host cells to increase their secretion of proinflammatory cytokines and matrix metalloproteinases (MMPs). This study aimed to determine the epithelial cell matrix metalloproteinase and interleukin-8 (IL-8) secretion upon exposure to fusobacteria.