Stimulation of epithelial cell matrix metalloproteinase (MMP-2,-9,-13) and interleukin-8 secretion by fusobacteria


Gursoy U. K. , Koenonen E., Uitto V. -.

ORAL MICROBIOLOGY AND IMMUNOLOGY, vol.23, no.5, pp.432-434, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1399-302x.2008.00453.x
  • Title of Journal : ORAL MICROBIOLOGY AND IMMUNOLOGY
  • Page Numbers: pp.432-434

Abstract

Background/aim: Bacterial pathogens involved in periodontal diseases exert their destructive effects primarily by stimulating the host cells to increase their secretion of proinflammatory cytokines and matrix metalloproteinases (MMPs). This study aimed to determine the epithelial cell matrix metalloproteinase and interleukin-8 (IL-8) secretion upon exposure to fusobacteria.