Role of thalamic diffusion for disease differentiation between multiple sclerosis and ischemic cerebral small vessel disease

ÖZTOPRAK B. , ÖZTOPRAK İ. , Topalkara K., Erkoc M. F. , ŞALK İ.

NEURORADIOLOGY, vol.57, no.4, pp.339-347, 2015 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1007/s00234-014-1479-z
  • Title of Journal : NEURORADIOLOGY
  • Page Numbers: pp.339-347


Cerebral small vessel disease (CSVD) and multiple sclerosis (MS) both harbor multiple, T2-hyperintense white matter lesions on conventional magnetic resonance imaging (MRI).We aimed to determine the microstructural changes via diffusion-weighted imaging (DWI) in normal appearing thalami. We hypothesized that the apparent diffusion coefficient (ADC) values would be different in CSVD and MS, since the extent of arterial involvement is different in these two diseases.