Akademik Veri Yönetim Sistemi
Quality Assurance and Safety of Crops & Foods, cilt.15, sa.4, ss.179-189, 2023 (SCI-Expanded)
Phenylketonuria (PKU) is a hereditary disease caused by the deficiency of phenylalanine (Phe) hydroxylase
enzyme or its cofactor tetrahydrobiopterin. Treatment involves a Phe-restricted diet, although food options are
limited. Soymilk, derived from soybeans, is a functional food with nutritional benefits. In this study, soymilk was
produced and hydrolyzed with protease of Aspergillus oryzae and papain, and then activated carbon was used to
remove Phe for PKU patients. The second-derivative spectrophotometry method was used to determine Phe content in soymilk. The results showed no significant difference in dry matter, fat, and crude fiber between soymilk
and Phe-extracted soymilk with respect to the control group (P < 0.05). Soymilk’s protein content was calculated
as 2.74% (w/w) and that of Phe-reduced soymilk as 1.94% (w/w). Similarly, consecutive Phe content was 40.53
mg/L and 5.09 mg/L. After hydrolization, the calculated Phe removal rate was 87.44% (w/w), and the protein content was reduced by 29.19% (w/w). The study demonstrates that Phe-reduced soymilk is s